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Texas Instruments AFE4460 Ultra-Small Integrated AFE is designed for optical biosensing applications, including heart-rate monitoring (HRM) and saturation of peripheral capillary oxygen (SpO2). The AFE4460 analog front-end supports up to 32 switching light emitting diodes (LEDs) and up to four photodiodes (PDs).
The TI AFE4460 Ultra-Small Integrated AFE features two LED drivers, each with 8-bit current control. The AFE offers a high dynamic range of transmit-and-receive circuitry that helps with sensing minimal signal levels. Additionally, the device can define up to 16 signal phase sets, with each phase set incorporating a combination of LED and Ambient phases.
Low noise offset DACs at the receiver inputs can be automatically controlled to cancel DC from Ambient and LED light. The current from each of the 4 PDs in each phase is converted into voltage by TIAs, filtered, and then digitized using a common ADC. The ADC code can be stored in a 256-sample FIFO block, which then can be read out using an SPI or I2C interface.









